Cyclobenzaprine: Generic, Uses, Side Effects, Dosages, Interactions & Warnings

Cyclobenzaprine: Generic, Uses, Side Effects, Dosages, Interactions & Warnings

Muscle spasm, local pain and tenderness, limitation of motion, and restriction in activities of daily living were evaluated. In three of these studies there was a significantly greater improvement with FLEXERIL than with diazepam, while in the other studies the improvement does flexeril make you gain weight following both treatments was comparable. Cyclobenzaprine reduced or abolished skeletal muscle hyperactivity in several animal models. Animal studies indicate that cyclobenzaprine does not act at the neuromuscular junction or directly on skeletal muscle.

Discuss these treatment options with a doctor to find the best medication for you. More serious side effects include hypersensitivity reactions. These allergic reactions can manifest as trouble breathing, severe rash, and swelling. Seek immediate medical attention if you experience these adverse effects.

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The Flexeril manufacturer information states that there are no adequate, well-controlled studies in pregnant women. Therefore, Flexeril should be used in pregnant women only if clearly needed. Ask your pharmacist any questions you have about refilling your prescription. Your dose will depend on the severity of your pain and the formulation of cyclobenzaprine you’re using. The immediate-release tablets last for about four to six hours, while the extended-release tablets last around 24 hours.

Dialysis is probably of no value because of low plasma concentrations of the drug. As management of overdose is complex and changing, it is recommended that the physician contact a poison control center for current information on treatment. As an illegal drug, cyclobenzaprine is known by the street names mellow yellow or cyclone. While not as popular among recreational drug users, it is known by addicts with experience abusing prescription drugs and a desire for sedative highs. It is not recommended to consume alcohol while on Robaxin or Flexeril. Alcohol can compound muscle-relaxant side effects such as drowsiness, dizziness, or loss of coordination.

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This means your doctor will need to get approval from your insurance company before your insurance company will pay for the prescription. If you have liver problems, your doctor may do a blood test to monitor how well your liver is working while you take this drug. You should not need a new prescription for this medication to be refilled. Your doctor will write the number of refills authorized on your prescription. Skelaxin and Flexeril can potentiate the effects of alcohol, barbiturates, and other CNS depressants, such as benzodiazepines, opioids, antihistamines, and sedative-hypnotics.

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I can easily see how someone might become addicted to it though. Stopping muscle relaxants suddenly can lead to withdrawal symptoms. Anyone with a history of substance abuse should mention this medical history to their doctor.

Some medicines can interact with cyclobenzaprine and cause a serious condition called serotonin syndrome. Ask your doctor before making any changes in how or when you take your medications. The incidence of drowsiness, the most frequent adverse reaction, was similar with both drugs. Concomitant use of monoamine oxidase (MAO) inhibitors or within 14 days after their discontinuation. Hyperpyretic crisis seizures, and deaths have occurred in patients receiving cyclobenzaprine (or structurally similar tricyclic antidepressants) concomitantly with MAO inhibitor drugs. This medication should only be used short-term (for 3 weeks or less) unless directed by your doctor.

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Do not increase your dose or use this drug more often or for longer than prescribed. Your condition will not improve any faster, and your risk of side effects will increase. Although cyclobenzaprine was found to have limited efficacy as an antidepressant, it proved very effective as a muscle relaxant. In 1977, it was approved by the US Food and Drug Administration (FDA) for treatment of muscle spasms. It is still manufactured by Merck & Company under the brand name Flexeril and is distributed by McNeil Consumer & Specialty Pharmaceuticals.

  • Ataxia, or severe and uncontrolled muscle spasms, is another symptom of toxicity.
  • However, cyclobenzaprine is one of the most studied muscle relaxers with strong evidence for its effectiveness.
  • This medication is sometimes prescribed for other uses; ask your doctor or pharmacist for more information.
  • Always discuss possible side effects with a healthcare professional who knows your medical history.

Cyclobenzaprine has moderate interactions with at least 43 different drugs. Robaxin can decrease the effectiveness of pyridostigmine bromide, a medication used to treat myasthenia gravis. Animal studies don’t always predict the way humans would respond. Therefore, this drug should only be used in pregnancy if clearly needed. Many insurance companies require prior authorization for this drug.

You might start to feel some of the effects of cyclobenzaprine within 20 to 30 minutes of taking it. The peak concentration varies, depending on what formulation you take. For example, the peak concentration for the extended-release pills is around seven hours. It works by blocking pain sensations that are sent to your brain.

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